5 Amino 1MQ

5-Amino-1MQ — also written as 5-Amino 1MQ, and by its full chemical name 5-amino-1-methylquinolinium — is a small-molecule quinolinium-salt research compound. It consists of a methylquinolinium heteroaromatic cation bearing an amino substituent at the 5-position and a methyl group at the ring nitrogen, and is typically supplied as the iodide salt. The compound has a cation molecular weight of approximately 159.21 g/mol (matching the [M]⁺ ion observed at m/z 159.000 on the lot LC-MS confirmation) and, as the iodide salt, an approximate salt-form molecular weight of 286.11 g/mol.

This product is supplied as an orange lyophilized powder — the characteristic color arises from the extended aromatic chromophore of the methylquinolinium ring system. The lot referenced here (5AMI-015-TPL) has a documented purity of 99.77% by HPLC with UV detection, with identity confirmed by LC-MS. Labeled vial size is 10 mg; net content per vial per the COA is 11.28 mg. Third-party characterization was performed by Freedom Diagnostics (USA). The product is intended exclusively for in-vitro laboratory research and analytical applications.

In the biochemistry research literature, 5-Amino-1MQ is characterized as a small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), a cytosolic methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl methionine (SAM) to nicotinamide.